M.D. New York Medical College (2012)
Internal Medicine Residency, Weill Cornell Medicine
Assistant Professor of Medicine, Weill Cornell Medicine (2024)
I am a medical oncology attending at Weill Cornell Medicine. Currently, I study cancer cell vulnerabilities that result from the loss of the tumor suppressor gene LKB1. I reside in New York City with my wife, Maya.
SELECTED PUBLICATIONS
“Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase.” Proceedings of the National Academy of Sciences of the United States of America. 2024
John R. Ferrarone, Jerin Thomas, Arun M. Unni, Yuxiang Zheng, Michal J. Nagiec, Eric E. Gardner, Oksana Mashadova, Kate Li, Nikos Koundouros, Antonino Montalbanod, Meer Mustafad, Lewis C. Cantley, John Blenis, Neville E. Sanjanad, and Harold Varmus.
“LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma.” Cancer discovery. 2023
Benjamin D. Stein; John R. Ferrarone; Eric E. Gardner; Jae Won Chang; David Wu; Pablo E. Hollstein; Roger J. Liang; Min Yuan; Qiuying Chen; John S. Coukos, Miriam Sindelar, Bryan Ngo, Steven S. Gross, Reuben J. Shaw, Chen Zhang, John M. Asara, Raymond E. Moellering, Harold Varmus, and Lewis C. Cantley.
“Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells.” Cell reports. 2022
Fraser D. Johnson, John Ferrarone, Alvin Liu, Christina Brandstadter, Ravi Munuganti, Dylan A. Farnsworth, Daniel Lu, Jennifer Luu, Tianna Sihota, Sophie Jansen, Amy Nagelberg, Rocky Shi, Giovanni C. Forcina, Xu Zhang, Grace S.W. Cheng, Sandra E. Spencer Miko, Georgia de Rappard-Yuswack, Poul H. Sorensen, Scott J. Dixon, Udayan Guha, Katja Becker, Hakim Djaballah, Romel Somwar, Harold Varmus, Gregg B. Morin, and William W. Lockwood.
“GCN2 kinase activation by ATP-competitive kinase inhibitors.” Nature Chemical Biology. 2021
Colin P. Tang, Owen Clark, John R. Ferrarone, Carl Campos, Alshad S. Lalani, John D. Choder, Andrew M. Intlekofer, Olivier Elemento and Ingo K. Mellinghoff.
“Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells.” eLife. 2018
Arun M Unni, Bryant Harbourne, Min Hee Oh, Sophia Wild, John R Ferrarone, William W Lockwood, Harold Varmus
“Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene U2af1.” Proceedings of the National Academy of Sciences of the United States of America. 2018
Dennis Liang Fei, Tao Zhen, Benjamin Durhame, John Ferrarone, Tuo Zhang, Lisa Garrett, Akihide Yoshimi, Omar Abdel-Wahab, Robert K. Bradley, Paul Liu and Harold Varmus.
